If you want to do this with a prepared statement, then you need to include the variable assignment in the original statement declaration.
If you want to use a stored routine it's easier. You can assign the return value of a stored function directly to a variable, and stored procedures support out parameters.
Examples:
Prepared Statement:
PREPARE square_stmt from 'select pow(?,2) into @outvar';
set @invar = 1;
execute square_stmt using @invar;
select @outvar;
+---------+
| @outvar |
+---------+
| 1 |
+---------+
DEALLOCATE PREPARE square_stmt;
Stored Function:
delimiter $$
create function square_func(p_input int) returns int
begin
return pow(p_input,2);
end $$
delimiter ;
set @outvar = square_func(2);
select @outvar;
+---------+
| @outvar |
+---------+
| 4 |
+---------+
Stored Procedure:
delimiter $$
create procedure square_proc(p_input int, p_output int)
begin
set p_output = pow(p_input,2);
end $$
delimiter ;
set @outvar = square_func(3);
call square_proc(2,@outvar);
select @outvar;
+---------+
| @outvar |
+---------+
| 9 |
+---------+
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