With Windows 10 x64, the setup is blocked by:
HKEY_LOCAL_MACHINESOFTWAREWow6432NodeMicrosoftNET Framework SetupNDPv4FullVersion
HKEY_LOCAL_MACHINESOFTWAREWow6432NodeMicrosoftNET Framework SetupNDPv4ClientVersion
Change both values temporarily to 4.0.30319
and the setup will let you continue. Make sure you edit the registry with elevated privileges, otherwise you will not be allowed to change the values.
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