You can definitely do this, the code looks like:
var objO = new ActiveXObject('Outlook.Application');
var objNS = objO.GetNameSpace('MAPI');
var mItm = objO.CreateItem(0);
mItm.Display();
mItm.To = p_recipient;
mItm.Subject = p_subject;
mItm.Body = p_body;
mItm.GetInspector.WindowState = 2;
p_recipient, p_subject & p_body being variables, passed in.
You need to ensure this is running on a webpage which users trust, as this will cause exceptions otherwise.
That is it needs to be in the right zone in IE, with the right settings configured for that zone.
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