I think importing using one of the methods mentioned is ideal if it truly is a large file, but you can use Excel to create insert statements:
="INSERT INTO table_name VALUES('"&A1&"','"&B1&"','"&C1&"')"
In MS SQL you can use:
SET NOCOUNT ON
To forego showing all the '1 row affected' comments. And if you are doing a lot of rows and it errors out, put a GO between statements every once in a while
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