First when you load your bitmap you make sure that you don't lose any image quality by settings options to argb_8888:
Options options = new Options();
options.inScaled = false;
options.inPreferredConfig = Bitmap.Config.ARGB_8888;
Bitmap pic = BitmapFactory.decodeResource(getResources(), R.id.pic, options);
When you scale the bitmap turn on the filter:
pic = Bitmap.createScaledBitmap(pic, screenW, screenH, true);
However if one streaches the image too much inevitably it degrades in quality.
When you use paint you can improve quality but lose on speed with turning on ditherig and filtering:
Paint paint = new Paint();
paint.setFlags(Paint.DITHER_FLAG);
paint.setFilterBitmap(true);
Finally the entire activity window could be set on argb_4444 instead on argb_8888 (OS < 2.3). You can chage this if you instert this line before setContentView:
getWindow().setFormat(PixelFormat.RGBA_8888);
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